Clinical Research

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Apollo Hospitals Educational and Research Foundation is the Site Management/ Solution Organization assisting the healthcare industry in conducting the drug discovery and development research activities.

Basic ResearchObjectives

  • To create a world respected entity for avenues in Clinical Research, covering activities from drug discovery, development, therapy and marketing to the Pharmaceutical and Biotechnology Industry
  • Ensure ethical conduct of clinical trials at the Apollo Hospital study sites as per ICH_GCP guidelines and ICMR guidelines of India.

Trial Experience

AHERF, the first Site Management Organization of Apollo Hospitals Group was initiated in 2000 with head quarters in Chennai. Mandated with one site office to begin with, AHERF has three established offices at Chennai, Hyderabad & New Delhi.

AHERF coordinates for the conduct of Investigator Initiative research studies for multiple specialties at various Apollo Hospital Centre’s across the country. To ensure the conduct of high-quality research, superior research data’s and protecting the safety of patients, AHERF conducts site monitoring activities periodically. We are also involved in validating of various diagnostic tools.


Our Strength

AHERF has a mix-up of GCP trained research team which consists of senior consultants, scientists, statisticians, scientific writers and clinical pharmacologists.

  • About the Project: To study the presence of endothelial cells in the blood samples of patients with Poly Cystic Ovarian Syndrome (PCOS), molecular characterization of the Endothelial Progenitor Cells (EPC) as a predictive marker for cardiovascular diseases is carried out by AHERF in collaboration with IIT Madras.
  • Status: The first phase of identification of EPCs is completed and second phase in which the characterization has to be evaluated is approved by the Ethics Committee and is awaiting funding applied to AHERF.
  • About the Project: To study the presence of endothelial cells in the blood samples of patients with Poly Cystic Ovarian Syndrome (PCOS), molecular characterization of the Endothelial Progenitor Cells (EPC) as a predictive marker for cardiovascular diseases is carried out by AHERF in collaboration with IIT Madras.
  • Status: The first phase of identification of EPCs is completed and second phase in which the characterization has to be evaluated is approved by the Ethics Committee and is awaiting funding applied to AHERF.
  • About the Project: A multi centric study to interpret various laboratory tests to identify disease states . To interpret these tests and to differentiate normal values from abnormal values, reference intervals are used. The observed laboratory value is compared to the reference range to make clinical and meaningful decisions.
  • Objectives:
    • To identify 95% reference interval for haematological and biochemical parameters.
    • Partitioning of the data for age, sex and recommend separate reference interval if significantly different.
    • To study regional difference, if any for these laboratory parameters.
  • Status: Study Completed
  • Results: Haemoglobin was less for the males and more so for the females.The low platelet count came in as a surprise. This findings has very important clinical implications as persons with platelet counts of 1,10,000 - 1,30,000 are subject to several investigations.Gender based partitioning is required for haemoglobin, packed cell volume, ESR, high density lipoprotein (HDL), triglycerides, serum creatinine, serum uric acid, ALT and GGTP. Age based reference intervals for ESR need to be considered.
  • Click here to download the project report.
  • Click here to download the project report.
  • Click here to download the project report.
  • Click here to download the project report.